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Association of the Framingham Risk Score with coronary CT angiography CAD-RADS Score.


Aureen  C. Foronda-Nieto,
Bryann Rene F. Toledano,
Harold L. Tan

Related Institution

Cardiovascular Radiological Sciences - Philippine Heart Center

Publication Information

Publication Type
Research Project
January 1-December 31, 2020


Background: Cardiovascular diseases are the leading cause of mortality worldwide and coronary artery disease (CAD) account for 19.98% of total deaths in the Philippines. Established risk factors for CAD also affect the Filipino population. With the development of the Coronary Artery Disease Reporting and Data System (CAD-RADS), which aim to aid radiologists and clinicians for management planning for patients with CAD, the aim of the study was to establish the correlation between the risk factors for CAD and the CAD-RADS score.

Method: This was a 6-year retrospective cross-sectional analytic study reviewing coronary CT angiography (CCTA) done at the Philippine Heart Center. There were 35 subjects included in the study. Patients with prior myocardial infarction, coronary artery stenting and coronary artery bypass graft were excluded from the study, as well as those with congenital heart condition. Clinical and demographic data were obtained for each subject, as well as the result of the conventional coronary angiogram. The CCTA was reviewed by a single radiologist and given CAD-RADS score form 0 to 5, with significant stenosis defined as those with CAD-RADS score of 3 or greater (50% stenosis).

Results: The association between the CAD-RADS score and the risk factors for CAD were evaluated. These risk factors include hypertension, diabetes, smoking history, family history of CAD and obesity. Subjects were identified into two groups, those with CAD-RADS score of 0 to 2 and those with CAD-RADS score of 3 to 5. No association was established between the CAD-RADS score and the risk factors for CAD. However, it was shown that an increase in the vessel stenosis of the left anterior descening and the right coronary arteries show an increased odds of having significant stenosis (50% stenosis).

Conclusion: Based on the study results, no association between the CAD-RADS score and the risk factors for CAD was established.

Physical Location

LocationLocation CodeAvailable FormatAvailability
Philippine Heart Center Medical Library CRF.R.026.20 Fulltext Print Format

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