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Radioactive Iodine Therapy in Hurthle Cell Thyroid Carcinoma .

Author

Serhan Y. Solaiman

Related Institution

Section of Nuclear Medicine - Cardinal Santos Medical Center

Publication Information

Publication Type
Book of Abstracts
Publication Sub Type
Compendium
Title
CSMC Research Abstract Compendium
Date
2014
Page(s)
2

Abstract

INTRODUCTION: Hurthle cell carcinoma is a rare type of thyroid cancer, related to the well-differentiated malignancies of the thyroid gland4, often considered as a subtype of follicular carcinoma. Management of Hurthle cell carcinoma remains controversial. Surgery is the treatment of choice and non-surgical treatment including radioactive iodine therapy yielded disappointing results. We describe a case of a patient diagnosed with Hurthle cell carcinoma who was subjected to radioactive iodine therapy.  


CASE PRESENTATION:  We report a case of a 50-year old female, with a 5-year history of right neck mass with no accompanying symptoms. Total thyroidectomy was done. Histopathology of the mass showed widely invasive Hurthle cell carcinoma with extensive vascular invasion and perithyroidal soft tissue extension in the right thyroid lobe. Whole body iodine-131 scan showed functioning thyroid remnants limited to the lower anterior neck. The patient underwent radioactive iodine therapy with a dose of 162.7 mCi 4 weeks post-operation. Post-ablation scan was done and showed functioning thyroid tissue remnants. She underwent external beam radiotherapy. Repeat CT scan 2 months post-RT showed absence of any thyroid tissue.  


DISCUSSION:  Surgery is the treatment of choice for Hurthle cell carcinoma. There are reports of patients who responded to radioactive iodine therapy. Whole body iodine scan is recommended and performed prior to the radioactive iodine therapy7. After one year, our patient remains asymptomatic with normal thyroid function tests.  


CONCLUSION:  Our patient with Hurthle cell carcinoma is asymptomatic one year after she had undergone surgery, radioactive iodine therapy, and radiotherapy. 

Physical Location

LocationLocation CodeAvailable FormatAvailability
Cardinal Santos Medical Center - Research Center Abstract Print Format

 
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