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Predictive value of heart rate variability during tilt table test for recurrence of syncope at Cardinal Santos Medical Center: a prospective study.


Maria Leonora Mendoza,
Jonah Amora

Related Institution

Cardiovascular Institute - Cardinal Santos Medical Center

Publication Information

Publication Type
Book of Abstracts
Publication Sub Type
CSMC Research Abstract Compendium


BACKGROUND: Syncope is a common cause of hospitalization among adult patients and although the prognosis of recurrent episodes is benign the quality of life of patients may be severely impaired because episodes may lead to injuries. Heart rate variability (HRV) is a noninvasive evaluation of autonomic nervous system activity. Studies have shown different results on the predictive value of HRV during tilt table test on the recurrence of syncope.

OBJECTIVE:  To evaluate the role of heart rate variability analysis during tilt table testing on predicting the recurrence of syncopal attack among patients at Cardinal Santos Medical Center (CSMC) undergoing tilt table test.

METHODS: A prospective cohort study of all adult (≥18 years) patients with documented syncope who had tilt table test at CSMC from 2015 to 2016 was done resulting to a total population of 47 subjects. Predictive value of the HRV during tilt table test for the recurrence of syncope was evaluated.  

RESULTS: A total of 47 patients were included in the study aged 19 years old to 85 years old, during the follow-up period 9 patients had recurrence of syncope during the 1st 3 months and none had recurrence during the succeeding 3 months. Mean R-R interval, SDNN, rMSSD and pNN50 were used for the analysis of HRV. All four heart rate variability measurements variables were found to be significant predictor variables of recurrence of syncope in both 1st 5 minutes and 1st 20 minutes measurements except for mean RR at 1st 20 minutes. At the 1st 5 minutes measurement, rMSSD has the highest area under the curve (AUC) coverage at 1.000, which means that 100.0% of variations in recurrence of syncope are properly identified or predicted by rMSSD at 1st 5 minutes. SDNN has it at 93.3%, pNN50 has it at 89.9%, but the lowest is Mean RR, which only predicted 75.1% recurrence of syncope.

CONCLUSION: HRV analysis during early phase of the tilt table test is a good predictor for the recurrence of syncopal attack in adults patients >18 years of age.  

Physical Location

LocationLocation CodeAvailable FormatAvailability
Cardinal Santos Medical Center - Research Center Abstract Print Format

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