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The first MIBG therapy in the Philippines.

Author

Patricia A. Bautista,
Jonas Francisco Y. Santiago

Related Institution

Department of Nuclear Medicine and PET - St. Luke's Medical Center

Publication Information

Publication Type
Journal
Publication Sub Type
Case report
Title
The Philippine Journal of Nuclear Medicine
Frequency
Semi-Annual
Publication Date
January-June 2015
Volume
10
Issue
1
Page(s)
24-27

Abstract

Neuroblastoma is an embryonal tumor of children that frequently presents with metastases. Our patient is a 6-year-old girl who was diagnosed to have neuroblastoma with diffuse metastatic disease throughout the skeleton as seen in her 123I-MIBG scan in the United States. 18F-FDG PET/CT scan was done in the Philippines after chemotherapy and gene therapy, and before 131I-MIBG therapy. No additional lesions were seen on PET.  131I-MIBG was then performed and an 131I-MIBG with SPECT/CT thereafter, which showed an increase in size and extent of the lesion in the head and a decrease in number of the skeletal metastases. New 131I-MIBG-avid posterior cervical lymph nodes were also localized through SPECT/CT. For this patient, a follow-up 123I/131I-MIBG scan would be more cost-effective in assessing response to therapy. Sectional imaging may be done to obviate the need for sedation of this young patient.

Physical Location

LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Library Box No.21 Fulltext Print Format

 
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