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An unusual case of lupus vulgaris and the use of interferon-gamma release assay (Quantiferon-TB Gold test) as an aid in supporting the diagnosis.

Author

Natividad Sandra D. Chua,
Maria VIctoria Rosabelle M. Rovira

Related Institution

Department of Dermatology - St. Luke's Medical Center

Publication Information

Publication Type
Journal
Publication Sub Type
Case report
Title
St. Luke's Healthcare Journal
Frequency
Semi-Annual
Publication Date
July-December 2016
Volume
11
Issue
2
Page(s)
94-98

Abstract

Lupus vulgaris is a cutaneous form of tuberculosis, which may persist for years unless treated. This is a relatively rare condition, the diagnosis of which can be challenging especially when it presents in areas that are not common predilection sites. In the western region, it is more often seen on the head and neck. Among Asians, it is more often seen on the trunk, knees, and elbows. It rarely occurs on the arms and legs. This is a case of a 55-year old Filipino woman with a solitary non-pruritic, non-tender, erythematous to dusky red plaque on the left anterior leg, which elicited an "apple-jelly" color on diascopy. Skin punch biopsy revealed granulomatous dermatitis. Purified protein derivative (PPD) and interferon-gamma release assay (Quantiferon TB-Gold) tests revealed positive results for tuberculosis infection. Based on morphology and laboratory results, she was diagnosed to have lupus vulgaris and was enrolled under the Department of Health's Tuberculosis-Directly Observed Treatment Short-course Program (TB-DOTS), and was treated successfully.

Physical Location

LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Library Box No. 35 Fulltext pdf (Request Document)

 
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