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Dermatological application of green tea (Camellia sinensis) in the Philippines: a systematic review of randomized clinical trials.

Author

Pearl Weena Marie E. Sabido,
Lonabel A. Encarnacion,
Natividad Sandra D. Chua,
Eleonor  B. Asuncion,
Katrina Carmina Y. Nisce-Anisco,
Mary Elizabeth S. Danga,
Lei Anne R. Hernandez,
Nicola N. Valbuena

Related Institution

Department of Dermatology - St. Luke's Medical Center

Publication Information

Publication Type
Journal
Title
St. Luke
Frequency
Quarterly
Publication Date
January-March 2014
Volume
9
Issue
1
Page(s)
63-72

Abstract

Background. Green tea, from the leaves of Camellia sinensis, is a rich source of polyphenols, especially (-)-epigallocatechin-3-gallate (EGCG). It has antioxidant, anti-inflammatory, antimicrobial, and anti-tumor properties, and is believed to have potential for various dermatological applications.


Objectives. This paper aims to assess the effects of green tea  or its components on the prevention or treatment of dermatologic conditions among Filipinos.


Methods. This is a systematic review of randomized controlled trials involving any form of green tea or its components as prevention or treatment of any dermatologic condition among Filipinos. Searching through electronic databases, reference lists of previous studies or reviews, and physical archives was done. At least two review authors independently applied the study criteria, extracted data and assessed methodological quality of studies. Discrepancies were resolved by discussion or by consulting a third review author. Study authors were contacted for missing information.


Results. Three published and 1 unpublished study with 252 participants, completed from 2003 to 2009, were reviewed. Each investigated the effects of green tea on different dermatological applications: namely, photoprotection, molluscum contagiosum, seborrheic dermatitis, and acne vulgaris. Each of these studies was  of high methodological quality. As each of them investigated different dermatological conditions, results were summarized descriptively according to dermatological condition.


Conclusion. There is limited to moderate evidence of regarding the effects of green tea on the prevention or treatment of the above conditions. This is primarily because only one study per dermatological condition was reviewed. However, as there is generally a trend to benefit with its topical use, and because it has thus far proven to be generally safe and well tolerated, its use as an adjunct in the prevention or treatment of the above conditions may be recommended.


 

References

1. Fuhrmann T, , Smith N, , Tausk F, . "Use of complementary and al- ternative medicine among adults with skin disease: updated results from a national survey" Journal of the American Academy of Dermatology 63(6): 1000-5, 2010
2. Sia IC, . "Medicinal plants for dermatologic conditions: The Philippine experience" Journal of the Philippine Dermatological Society 3(1): 6-7, 1994
3. Aparece UB, . "Lunas: The " Philippine Ouarterly of Culture & Society 34, 135-87, 2006
4. (). . Retrieved from: http://www.doh.gov.ph/pitahc/
5. Mitscher LA, , Jung M, , Shankel D, , Dou J, , Steele L, , Pillai SP, . "Chemoprotection: A Review of the potential therapeutic antioxidant properties of green tea (Camellia sinensis) and certain of its constituents." Medicinal Research Reviews 17(4): 327-65, 1997
6. (2001, November 30). Green tea (Camellia sinensis). Alternative Medicine Review Monographs. . Retrieved from: http://www.thorne.com/media/alternative_medicine_review/monographs/GreenTeaMono.pdf
7. Hsu, S . "Green tea and the skin (Review)" Journal of the American Academy of Dermatology 52, 1049-59, 2005
8. Katiyar SK, , Perez A, , Mukhtar H, . " Green tea polyphenol treat- ment to human skin prevents formation of ultraviolet light B-induced pyrimidine dimers in DNA" Clin Cancer Res 6, 3864-9, 2000
9. Katiyar SK, , Afaq F, , Perez A, , Mukhtar H, . "Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress" Carcinogenesis 22(2): 287-94, 2001
10. Mukhtar H, , Ahmad N, . "Mechanism of cancer chemopreventive activity of green tea" Proc Soc Exp Bioi Med 220(4): 234-8, 1999
11. Lu Y, , Lou Y, , Xie J, , Peng Q, , Liao J, , Yang CS, , Huang M, , Conney AH, . "Topical applications of caffeine or (-)-epigallocatechin gallate (EGCG) inhibit carcinogenesis and selectively increase apoptosis in DYB-induced skin tumors in mice." Proc Natl Acad Sci USA 99(19): 12455-1246, 2002
12. Boehm K, , Borrelli F, , Ernst E, , Habacher G, , Hung SK, , Milazzo S, , Horneber M, . "Green tea (Camellia sinensis) for the prevention of cancer" Cochrane Database of Systematic Reviews (3): 2009
13. Chiu AE, , Chan JL, , Kern DG, , Kohler S, , Rehmus WE, , Kimball AB, . "Double-blinded, placebo-controlled trial of green tea extracts in the clinical and histologic appearance of photoaging skin" Dermatol Surg 31, 855-9, 2005
14. Hamilton-Miller JM, . "Antimicrobial properties of tea (Camellia sinensis L.)" Antimicrob Agents Chemother 39(11): 2375-2377, 1995
15. Vijaya K, , Ananthan S, , Nalini R, . " Antibacterial effect of theaflavin, polyphenon 60 (Camellia sinensis) and Euphorbia birta on Shigella spp. -a cell culture study" J Ethnopharmacol 49(2): 115-8, 1995
16. Tatti S, , Stockfleth E, , Beutner KR, , Tawfik H, , Elsasser U, , Weyrauch P, , Mescheder A, . "Polyphenon E®: a new treatment for external anogenital warts" British Journal of Dermatology 162(1): 176-84, 2009
17. Tzellos TG, , Sardeli C, , Lallas A, , Papazisis G, , Chourdakis M, , Kouvelas D, . "Efficacy, safety and tolerability of green tea catechins in the treatment of external anogenital warts: a systematic review and meta-analysis." Journal ofthe European Academy of Dermatology and Venereology , 2010
18. Meltzer SM, , Monk BJ, , Tewari KS, . "Green tea catechins for treatment of external genital warts" American Journal of Obstetrics and Gynecology 200(3): 233.e1-233, 2009
19. Angeles CB, , Katiyar SK, , Ampil ID, , Arcilla BB, . "Prevention of UVB-induced erythema with topical treatment of green tea extract: A randomized, placebo and active controlled clinical trial" J Phil Dermatol Soc 13(1): 8-15, 2004
20. Cabillos MR, , Leelin-Sarrosa DM, , Verallo-Rowell VM, . "Green tea extract cream (epigallocathechin gallate) in the treatment of molluscum contagiosum: A randomized, double-blind, vehicle-controlled trial" J Phil Dermatol Soc 12(2): 21-7, 2003
21. Gan-Wong J, , Salcedo-Rubio E, , Barcelona-Tan J, . "Comparison between 3% green tea (Camellia sinensis) extract in cream and 4% benzoyl peroxide cream in the treatment of acne vulgaris: A randomized, double-blind, clinical trial" J Phil Soc Cut Med 4(1): 83-95, 2003
22. Pajaro-Lorico MJL, , Dizon J, , Carpio BDL, , Regalado-Morales E, . Green tea lotion (2% epigallocatechin gallate) as alternative therapy for seborrheic dermatitis: A randomized, triple-arm clinical trial.. 2009. Ospital ng Maynila Memorial Medical Center,
23. Yao-Dy N, , Cabigao G, , Buenviaje-Beloso M, . Comparison between 3% green tea extract (Camellia sinensis) cream and 4% hydroquinone cream in the treatment of melasma: A randomized, double blind, controlled study. 2004. Jose R. Reyes Memorial Medical Center,
25. No JK, , Soung DY, , Kim YJ, . "Inhibition of tyrosinase by green tea components" Life Sci 65(21): 241-6, 1999

Physical Location

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Philippine Council for Health Research and Development Box. No. 35 Fulltext pdf (Request Document)

 
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