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Effect of traditional risk factors on the homocysteine levels in unstable angina and non- st elevation myocardial infarction.


Jose B. Nevado Jr.,
Marcelo B. Severino Imasa

Related Institution

Department of Science and Technology, DOST

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Publication Information

Publication Type
Research Project


Increased blood homocysteine level is a risk fsctor for unstable angina and non-ST elevation myocardial infarction (NSTEMI). This study seek to determine the effect of conventional cardiovascular risk factors - smoking, diabetes, hypertension, advanced age, and dyslipidemia - on homocysteine levels of patients with unstable angina and non-ST elevation myocardial infarction (NSTEMI). Data were taken from 219 patients with unstable angina and non-ST elevation myocardial infarction (NSTEMI) in the past 2 weeks wh owere included in a folic acid supplementation trial. Baseline homocysteine level was positively correlated with age (p=0.008) and significant smoking hidtory, both curtrent and past (p=0.028), but negatively correlated with body mass index (BMI) (p=<0.001). However, there was no significant correlation detected between the risk factors and high homocysteine levels (>16 umol/li). No significant association was detected with diabetes mellitus, hypertension, dyslipidemia and sex. In conclusion, advanced age and smoking are associated with increased homocysteine levels, and BMI is associated with decreased homocysteine levels, in patients with unstable angina and NSTEMI.

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Philippine Council for Health Research and Development Library RDR 685.A6 N48 / 391 Fulltext pdf (Request Document)

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