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Oral pharmacological treatment of X-linked dystonia parkinsonism: Successes and failures.


Roland Dominic G. Jamora,
Roland Dominic G. Jamora,
Cid Czarina E. Diesta,
Paul Matthew D. Pasco,
Lillian V. Lee

Related Institution

Department of Neurosciences, College of Medicine, - Philippine General Hospital - University of the Philippines-Manila

Movement Disorders Center and Section of Neurology, International Institute for Neurosciences, - St. Luke's Medical Center, Quezon City, Metro Manila, Philippines

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Publication Information

Publication Type
Sub Type
Journal Article, Original
The Philippine Journal of Neurology
Date of Publication
August 2012


There is a paucity of published literature on the different oral medications tried for X-linked dystonia parkinsonism (XDP). In practice, most XDP patients are tired on medication typically used for patients with generalized dystonia. These drugs include anticholinergic agents, baclofen, clonazepam and other ben-zodiazepines, tetrabenazine, and clozapine. Although several articles have shown that these classess of drugs are beneficial for patients with generalized dystonia, none been systematically studied specifically for XDP patients. We are currently conducting the first randomized, placebo-controlled trial on the medications that have been used in XDP.


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Philippine Council for Health Research and Development Library Box no.54 Fulltext Print Format

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