i
Report an error   
Advanced Search


Correlation of nasal smear eosinophilia with severity classification of allergic rhinitis among Filipino children.

Author

Jocelyn S. Doroin,
Cecile D. Cabangal-Gumarin,
Adelina D. Pring-Abarintos,
Eileen G S. Talusan,
Madeleine W. Sumpaico

Related Institution

Section of Allergy and Clinical Immunology - University of the Philippines-Philippine General Hospital

See More

Publication Information

Publication Type
Journal
Publication Sub Type
Journal Article, Original
Title
Philippine Journal of Allergy, Asthma and Immunology
Frequency
Semi-Annual
Publication Date
May-December 2003
Volume
9
Issue
2
Page(s)
16-24

Abstract

BACKGROUND: Allergic Rhinitis is a clinical hypersensitivity of the nasal mucosa to foreign substances mediated through IgE antibodies. During symptomatic periods, eosinophils predominate in the nasal secretions of patients with allergic rhinitis. These can be demonstrated using a simple technique using the Wrights stain. This study aims to determine the relationship between nasal smear eosinophilia with severity classification of allergic rhinitis among Filipino children.


METHODS: Ninety-one symptomatic Filipino children suffering from allergic rhinitis were included in this study. All patients had a positive skin test result to at least one aeroallergen. Nasal smear samples were taken from both nostrils and specimens were stained using the Wrights method to demonstrate eosinophils.


RESULTS: Nasal smear eosinophilia correlates with the severity classification of allergic rhinitis among symptomatic pediatric patients (p=0.0001). Detection of /- 12 eosinophils per 10 HPF in nasal smears can be a predictor of a mild disease with a 90.9 percent sensitivity and 70.7 percent specificity. Eosinophil count of /- 17 per 10 HPF is an indicator of a severe condition with a 96.3 percent sensitivity and 87.5 percent specificity.


CONCLUSION: The results suggest that nasal smear eosinophilia correlates with the severity classification of allergic rhinitis among symptomatic Filipino children. Eosinophil determination in nasal smears can be utilized both to confirm the diagnosis and to indicate the severity of allergic rhinitis. (Author)

Physical Location

LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Library Fulltext Print Format
Philippine Council for Health Research and Development Fulltext pdf (Request Document)

 
Loading…
©2022 HERDIN PLUS. All rights reserved. | Contact Us | Keep up to date