Author
Anthony Manlulu ,
Jonathan Nolasco ,
Edgar Palacol ,
Imelda Palacol ,
Stephanie Santos ,
Related Institution
Section of Thoracic and Cardiovascular Surgery, Department of Surgery, - St. Luke's Medical Center , Quezon City, Metro Manila, Philippines
Publication Information
Sub Type
Journal Article, Original
Title
Philippine Journal of Surgical Specialties
Date of Publication
January-March 2003
Abstract Vascular reconstruction utilizing autologous vein grafts may require additional incisions for harvesting. Synthetic prosthetic grafts are associated with an increased risk of infection.OBJECTIVE: We present an alternative method of aortic reconstruction using autologous fascia and peritoneum as a patch graft.METHODS: Fascia-peritoneal patch grafts were used to repair an infrarenal aortic defect in 5 landrace pigs. The subjects underwent re-laparotomy at specific intervals with excision of the grafted aortic segment. The specimens were examined utilizing hematoxylin and eosin stain, special stains for elastin (Weigerts stain), collagen (Massons Trichrome stain) and immunohistochemical stain for factor VIII.RESULTS: In all specimens, no thrombosis was noted and graft patency was 100 percent. Endothelialization was apparent at 7 days, however, factor VIII stain failed to light up the endothelial cells in all specimens. Elastin and collagen formation were noted in the patch graft at 28 days as shown in Weigerts and Massons Trichome stain.CONCLUSION: Fascia-peritoneal patch graft can be used as an alternative method of aortic reconstruction with excellent patency rates and no wound complications.
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