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Comparative study between 1-propanol, 2-propanol & mecetronium ethyl sulfate (sterillium) hand-rub and chlorhexidine gluconate (microshield) hand-scrub for surgical hand disinfection.

Author

Martin Ranellus P. Samson,
Martin Anthony A. Villa,
Jeffrey J. Domino,
Deogracias Alberto G. Reyes,
Edgardo R. Cortez

Related Institution

Department of Surgery - St. Luke's Medical Center

Publication Information

Publication Type
Journal
Publication Sub Type
Journal Article, Original
Title
Philippine Journal of Surgical Specialties
Frequency
Quarterly
Publication Date
April-June 2001
Volume
56
Issue
2
Page(s)
65-68

Abstract

Two popular hand disinfectant solutions based on different principles and mechanisms of action were compared as to their ability to eradicate aerobic bacteria and their duration of action. Forty participants were chosen randomly forming two groups. Group A employed the hand scrub method using chlorhexidine (Microshield) and Group B the hand rub method using 1-propanol, 2-propanol and mecetronium ethyl sulfate (Sterillium). Culture swabs were taken from a 25 sq cm area over the palm before, immediately after and two hours after disinfection. The results showed an average of 50,000 colony forming units (CFUs) of bacterial species among the participants before hand disinfection. No bacterial growth was noted immediately after hand disinfection. However, two hours later there were 8 out of 20 (40 percent) positive growth for Group A (30,000 to 70,000 CFUs) and 4 out of 20 (20 percent) positive growth for Group B (40,000 to 70,000 CFUs). T-test statistical analysis revealed no significant difference between the two groups. (Author)

References

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8. Osmunden, P E. "Contact dermatitis of chlorhexidine" Contact Dermatitis 8(2): 81-83, 1982. Retrieved from: http://www.ncbi.nlm.nih.gov/pubmed/6461508
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10. Kalmar, P , Steinhagen, R H. "Surgical hand disinfection using alcoholic rubbing disinfectants" Chirurg 55(4): 280-287, 1984. Retrieved from: http://www.ncbi.nlm.nih.gov/pubmed?term=kalmar%20p%2C%20steinhagen%20rh

Physical Location

LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Library Box No. 6 Fulltext pdf (Request Document)

 
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