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Utilization of four-dimensional ultrasound in the detection of neoplastic liver masses: A preliminary study.

Author

Ismael A. Lapus,
Diana A. Payawal,
Rodney L. Fernan,
R R. Reyes

Related Institution

Abstract

Background: Significant advances have been introduced recently in various fields of medical technology one of these is the Four-Dimensional Ultrasound or 4-D US. The 4-D US is an imaging machine used in the detection of liver masses.

Objective: To determine the sensitivity and specificity and the likelihood ratios of 4-D US in comparison to Two-Dimensional US (2-D US) and Magnetic Resonance Imaging (MRI) in the detection of neoplastic liver masses.

Methodology: This is a preliminary cross-sectional study conducted at the Cardinal Santos Medical Center. Patients with a reading of a liver mass or suspicious liver mass on 2-D US underwent MRI and 4-D US. Tumor morphology and intralesional vascular involvement were noted. Histopathologic correlation was done on all patients.

Results: Seventeen patients were identified to have a liver mass or a suspicious liver mass on 2-D US. Of these, 13 were found to have neoplastic and non-neoplastic mass on 2-D US and 4-D US, while 14 patients were seen to have neoplastic mass based on MRI findings. When correlated histopathologically sensitivity and specificity of 4-D US results showed 92 percent and 75 percent with a likelihood ratio of 3.7 and 0.11 for positive and negative tests. 2D-US had 85 percent and 50 percent sensitivity and specificity with a likelihood ratio of 1.7 and 0.3 for positive and negative tests. MRI showed 100 percent sensitivity and 75 percent specificity with a likelihood ratio of 4 and 0 for positive and negative tests. Intralesional involvement was only seen on 4D-US.

Conclusion: Preliminary results showed that 4-D US is superior compared to 2-D US and is almost comparable with MRI in the detection of neoplastic liver masses.

Objectives

To determine the sensitivity and specificity and the likelihood ratios of 4-D US in comparison to Two-Dimensional US (2-D US) and Magnetic Resonance Imaging (MRI) in the detection of neoplastic liver masses.

Physical Location

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Philippine Council for Health Research and Development Library Box No. 99 Fulltext Print Format

 
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