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Infective endocarditis, SLMC experience, a preliminary report.


 Fabra-Coronel, Remed,
 Cruz, Misael C,
 Baleva, Ma Emilia A

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Publication Information

Publication Type
Philippine Journal of Internal Medicine
1998 Jul-Aug
Publication Date


Objective: The diagnosis of Infective Endocarditis is based upon a constellation of clinical findings rather than upon a single definitive test results
The study aim to describe the demographics and clinical features of definite cases of Infective Endocarditis St. Lukes Medical Center over a 2 1/2 year study period
Study Design: Retrospective Study
Setting: Tertiary Center of St. Lukes Medical Center Infectious Disease Service and Heart Institute, Section of Non Invasive Cardiology
Participants: 14 cases suspected of Infective Endocarditis, 10 males, 4 females age range of 15-60 years old. Definite cases of Infective Endocarditis included in the analysis of data based on Dukes Classification
Interventions: Echocardiography was done to all patients. Sulbactam-Ampicillin 12 gms./day with Aminoglycosides given to patients. 2 out of 4 cases with prosthetic valve endocarditis were subjected to undergo cardiac surgery of mitral valve repair
Results: Our study showed a predominance of male (10/14), over female (4/14) with Infective Endocarditis. The most common pre-existing lesion was Rheumatic Heart Disease with mitral regurgitation, 41.6 percent. Among the organism isolated on blood culture, the most common were gram (+) cocci namely, B hemolytic Streptococci 33.3 percent, followed by Staphylococcus epidermidis 16.6 percent. However, 7 out of 14 yielded no organism, on blood culture. Most common source was related to Cardiovascular operations, 28.5 percent. Mortality rate was 50 percent
Conclusion: Fourteen cases identified at St. Lukes Medical Center from January 1994 to May 1996 with definite Infective Endocarditis based on a Dukes Criteria. With the scarcity of data in the Philippines, there is a need for a lengthy pursuits regarding awareness of the seriousness of the disease, considering an overall mortality rate of 50 percent (7/14) for the future endeavor. (Author)

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Philippine Council for Health Research and Development Library Abstract Print Format

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