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Myocardial infarction in the young: An analysis of the risk factors and coronary angiogram.


Erwin O. Del Rosario,
Susan H. Dilan

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Publication Information

Publication Type
Publication Sub Type
Journal Article, Original
St. Luke's Medical Journal
Publication Date
July-December 1995


PURPOSE: To determine the significant risk factor among young Filipinos (less than forty years of age) and correlate the number of risk factors to the number of coronary arteries involved.
PATIENTS AND METHODS: Thirty-three young patients admitted at St. Lukes Medical Center from January, 1993 to October, 1994 diagnosed to have myocardial infarction who subsequently underwent coronary arteriography using transfemoral Seldingers technique were included in study. Risk factors identified the following: (1) smoking, (2) family history of coronary artery disease, (3) diabetes mellitus, (4) hypertension, (5) hypercholesterolemia, (6) hypertriglyceridemia, (7) low HDL, (8) elevated LDL, (9) left ventricular hypertrophy by 2-D echocardiography and/or electrocardiography. Frequency distribution was used to determine presence of variables. Chi-square was used to test the association between one variable and vessel involvement. Multiple regression was then used to test the association between variables and vessel involvement.
RESULTS: Occurrence of myocardial infarction for Filipinos less than 40 years of age were all males. Analysis of the variables show that smoking of at least five cigarettes per day at least a year was the most common and is a significant risk factor (69/7%). In the multiple regression analysis, low HDL plays a major role and is the predictive factor in the development of coronary artery disease (Sig. T=0.0151 with p values 0.05). A single vessel involvement was the most prevalent (51.5%) with the left anterior descending artery as the most frequently involved artery (90%).
CONCLUSION: In Filipinos less than 40 years of age, low HDL is a predictive factor with both smoking and low HDL as a significant risk factors in the development of myocardial infarction, involving mostly the left anterior descending artery.


1. Carlos, J L, Dizon, F . "Identification of the high risk patient with acute myocardial infarction during the hospital phase" MMC Proc , 18-23, 1990
2. Gordon, T , Kannel, W B, McGee, D . "Deand and coronary attacks in men after giving up cigarette smoking: A case report from the Frammingham study" Lancet 2, 1345, 1974
3. Truett, J , Cornfield, J , Kannel, W B. "A multivariate analysis of risk of coronary heart disease in Frammingham" J Chr Dis 20, 511, 1967
4. Behar, S . "Long term prognosis after myocardial infarction in patients with left ventricular hypertrophy on the ECG" Am J Cardiol 69, 985-990, 1992
5. Ramos, E . "Total cholesterol and lipoprotein profile in Filipinos with and without coronary heart disease" Phil J Cardiol 16(1): 1987
6. Dolder, M A, Oliver, M F. "Myocardial infarction in young men. Study of risk factors in nine countries" Br Heart J 37, 493-498, 1975
7. Keys, A . "Coronary heart disease in seven countries" Circ 41((Suppl 1)): 211, 1970
8. Colditz, G A, Rimm, E B, Willett, W C. "A prospective study of parental history of myocardial infarction and coronary disease in men" Am J Cardiol 67, 933-938, 1991
9. "Infarction Survival Study Group. Interim report on infarct survival in the Philippines" ,
10. Walker, W J, Gregaratos, R T. "Myocardial infarction in young men" Am J Cardiol 19, 339-343, 1967
11. Barranachea, E C. "The prevalence of hyperglycemia in acute myocardial infarction" Phil J Intern Med 23, 255-258, 1985
12. Raglioni, N C. "Role of family history in the patients with myocardial infarction" Circ 85(6): 2065-2071, 1992
13. Yater, A H, Spring, B , Geisler, R P. "Coronary artery disease in the young" Am Heart J 36, 334-372, July 1995-December 1995
14. Soto, R C, Villaroman, J S, Durante, M M. "The relationship of risk factors to the severity of coronary artery disease" Phil J Cardiol 7, 89-93, 1979
15. "Fifth report on the joint national committee on detection, evaluation and treatment of high blood pressure (JNC V)" Arch Int Med 153, 153-182, July 1995-December 1995
16. "Adult Treatment Group. Summary of the Second Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation and Treatment of High Blood Cholesterol in Adults (ATP II)" JAMA 269(23): 3015-3023, July 1995-December 1995
17. Rose, G A , Blackburn, H . "CV survey methods" WHO monograph series no. 58 , 1982
18. Bergstrand, R , Verdin, A , Wilhelmson, C . "Myocardial infarction among men below age 40" Br Heart J 40, 783-788, July 1995-December 1995
19. Moreno, F L, Garayblas, V E, De la Paz, . "Acute myocardial infarction in young Filipinos" Phil J Int Med , 161-174, 1980

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