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Dobutamine echocardiography in the diagnosis of coronary artery disease.


 Balleza Y,
 Sulit Y,
 Angbengco JM,
 Calleja H,
 Lastimosa R

Related Institution

Department of Echocardiography and Doppler and Cardiac Catheterization - St. Luke's Medical Center

Publication Information

Publication Type
J Philipp Soc Echocardio
1993 Jan-Jun
Publication Date


DSE in the diagnosis of coronary disease is based on the premise tht dobutamine could induce evidence of LV asynergy. The purpose of this study was to correlate wall motion abnormality by DES and coronary artery lesion by coronary angiography and to determine the sensitivity, specificity and predictive values of DSE in CAD in relation to coronary angiography
One hundred thirty five (135) patients underwent DSE using a protocol of incremental increase in dobutamine infusion and a maximun dose of 40 mcg/kg/min or upon reaching MPR of more that 70%. Echocardiographic examinations were done using the ASE recommendations. Fifty one patients (35 males and 15 females) underwent coronary angiography with 50% stenosis in any one of the epicardial coronary arteries as signficant CAD
Our results showed that wall motion abnormality induced by DSE is correlated with coronary lesions by coronary angiography with values of 97.44%, 83.33%, 95% and 90.91% sensitivity, specificity, positive predictive value and negative predictive value respectively. Our results agree with reports in literature that dobutamine echocardiography has good sensitivity and specificity in the detection of CAD. (Conclusion)

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