i
Report an error   
Advanced Search


Phenomenology of "lubag" or X-linked dystonia-parkinsonism.

Author

Andrew Singleton,
Joven Cuanang,
Joel Advincula,
Katrina Gwinn-Hardy,
Paul Pasco,
Dena Hernandez,
Filipinas F. Natividad,
Virgilio Gerald H. Evidente,
Amado San Luis,
Raymund Esteban,
John Hardy,
Jhoe Anthony Alfon

Related Institution

National Institutes of Health, Baltimore, Md

U.E.R.M. Memorial Medical Center

See More

Publication Information

Publication Type
Journal
Publication Sub Type
Others
Title
Movement Disorders
Frequency
Unknown
Publication Date
June 2002
Volume
17
Issue
6
Page(s)
1271-1277

Abstract

X-linked dystonia-parkinsonism (XDP), or Lubag syndrome, is known to cause progressive dystonia, with or without parkinsonism, among Filipino male adults with maternal roots from the Philippine island of Panay. We present cinematographic material of 11 cases of Lubag carrying the XDP haplotypes who manifest with a wide spectrum of movement disorders, including dystonia, tremor, parkinsonism, myoclonus, chorea, and myorhythmia. Because of overlapping features, Lubag patients are commonly misdiagnosed as idiopathic dystonia, essential tremor, Parkinson's disease, or Parkinson's-plus syndromes. Thus, it is imperative to elicit an exhaustive family history in any Filipino male adult who presents with a movement disorder. (Author)

Physical Location

LocationLocation CodeAvailable FormatAvailability
Philippine Council for Health Research and Development Library Fulltext Print Format
U.S. National Library of Medicine: PubMed/Medline Abstract External Link (View)
U.S. National Library of Medicine: PubMed/Medline Fulltext pdf (Request Document)

 
Loading…
©2022 HERDIN PLUS. All rights reserved. | Contact Us | Keep up to date