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A Phase 2, Randomized, Double-dummy, Observer-Blind, Study to Evaluate the Safety, Tolerability, and Immunogenicity of PTX-COVID19-B Compared to Pfizer-BioNTech COVID-19 Vaccine in Healthy Seronegative Adults Aged 18 to 64 Years.
To evaluate the safety and tolerability of 40 μg PTX-COVID19-B in healthy seronegative adults 18-64 years of age.
A Phase II, Randomized, Double-Blind, Placebo-Controlled Dose-Ranging, Parallel and Adaptive Study to Evaluate the Efficacy and Safety of Enpatoran in Systemic Lupus Erythematosus and in Cutaneous Lupus Erythematosus (Subacute Cutaneous Lupus Erythematosus and/or Discoid Lupus Erythematosus) Participants Receiving Standard of Care
Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosus (Subacute Cutaneous Lupus Erythematosus and/or Discoid Lupus Erythematosus)
GlobalSurg-CovidSurg Week: Determining the optimal timing for surgery following SARS-CoV-2 infection – Philippine General Hospital data
30 day Post-operative Mortality
Safety, Tolerability, Efficacy and Pharmacokinetics of Imipenem/Cilastatin/Relebactam (MK-7655A) in Pediatric Participants With Gram-negative Bacterial Infection (MK-7655A-021)
Suspected or Documented Gram-negative Bacterial Infection
A Randomized, Observer-blind, Phase 2/3 Adaptive Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of Different Dose Levels of Ad26.COV2.S Administered as a One- or Two-dose Regimen in Healthy Adolescents From 12 to 17 Years Inclusive
Coronavirus Disease-2019 (COVID-19) Prevention
The Prevalence of Renal Hyperparathyroidism among Dialysis-Requiring Patients
The primary outcome in this study is the prevalence of Renal hyperparathyroidism.
Local prevalence of Renal hyperparathyroidism and correlation of intact Parathyroid hormone (iPTH) levels, Vitamin D, serum Calcium and serum Phosphorus with the risk factors identified among dialysis-requiring patients.
A Phase 2, Randomized, Double-blind, Placebo-controlled, Double-dummy, Multicenter Trial Assessing the Efficacy and Safety of Two Dose Regimens of JNJ-64281802 for the Prevention of Dengue Infection
The purpose of this study is to evaluate the prophylactic effect of JNJ-64281802 with respect to the prevention of laboratory-confirmed dengue virus (DENV) infection up to last day of dosing among participants who have no evidence of current DENV infection at baseline.
A Global Study to Assess the Effects of Durvalumab +Domvanalimab Following Concurrent Chemoradiation in Patients with Stage III Unresectable Non-Small Cell LungCancer (PACIFIC 8)
PFS is defined as time from randomisation until progression per RECIST1.1 as assessed by BICR, or death due to any cause
•PFS measured by HR
Locally advanced (Stage III), unresectable Non-small cell lung cancer
A Phase 2b, Randomized, Double-Blind, Multicenter, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Treprostinil Palmitil Inhalation Powder in Participants with Pulmonary Arterial Hypertension
Pulmonary Arterial Hypertension (PAH)
INNOVATE- Inovio INO-4800 Vaccine Trial for Efficacy